Abstract: |
The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), invites new applications from institutions with multidisciplinary research teams to participate in the development of new reagents for Toll-like and other innate immune pattern recognition receptors (PRRs). The goal of this Funding Opportunity Announcement (FOA) is to support the development and wide distribution of reagents to the scientific community for use as research tools to study the expression and physiological functions of PRRs in humans and animal model systems. Examples of reagents to be created and characterized include antibodies, soluble receptors, fusion proteins, RNA-based inhibitors, and small molecules. Awardees will form an interactive steering committee to share information, expertise, and resources leading to the rapid development of novel research tools. In addition, an external advisory group will be formed by the NIAID after award to provide critical advice on reagent prioritization and changes in experimental methods or directions. The overall goal of this program is to facilitate the development of new vaccines, therapeutics, and diagnostics for the prevention and treatment of existing, emerging, and re-emerging infectious diseases. |
