Abstract: |
The Biomolecular Systems Cluster emphasizes the structure, function, dynamics, interactions, and interconversions of biological molecules. The context for such studies can range from investigations of individual macromolecules to the large-scale integration of metabolic and energetic processes. Research supported by this cluster includes development of cutting-edge technologies integrating theoretical, computational, and experimental approaches to the study of biological molecules and their functional complexes; mechanistic studies of the regulation and catalysis of enzymes and RNA, and higher-order characterization of the biochemical processes by which all organisms acquire, transform, and utilize energy from substrates. This cluster emphasizes the importance of multidisciplinary research carried out at the interfaces of biology, physics, chemistry, mathematics and computer science, and engineering. |
